+1 203-737-4151

stefania.nicoli@yale.edu

Nicoli Lab
Yale Cardiovascular Research Center
Cardiology-Internal Medicine at Yale University
 New Haven, CT 
 Development and miRNAs
The precise specification and differentiation of tissue stem/progenitor cells during development is crucial to the establishment and maintenance of all cell lineages throughout adult life. Our laboratory utilizes zebrafish development as a model to discover the molecular mechanisms driving the processes necessary to build the embryonic cardiovascular and neuronal  systems and to maintain the homeostasis of these tissues. The major focus of our research is microRNAs (miRNAs), a class of non-coding RNAs whose pervasive roles in stem cell and tissue specification make them ideal candidate regulators of development. 
  1. miRNA-mRNA interactome
    miRNA-mRNA interactome
  2. Neurogenesis
    Neurogenesis
  3. Vascular Development
    Vascular Development
  1. Development
  2. Vascular biology
  3. miRNAs